Predictors of the use of complementary and alternative medicine (CAM) by women at high risk for breast cancer

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• 作者：K.M. Field ; M.A. Jenkins ; M.L. Friedl ; er ; J.M. McKinley ; M.A. Price ; P. Weideman ; L.A. Keogh ; S.A. McLachlan ; G.J. Lindeman kConFab Investigators ; J.L. Hopper ; P.N. Butow ; K.A. Phillips
• 关键词：Complementary medicine ; Alternative medicine ; CAM ; Familial ; BRCA1 ; BRCA2 ; Breast cancer ; Ovarian cancer ; Chemoprevention ; Tamoxifen
• 刊名：European Journal of Cancer
• 出版年：2009
• 出版时间：March 2009
• 年：2009
• 卷：45
• 期：4
• 页码：551-560
• 全文大小：252 K

文摘

Background

Few data exist regarding the use of complementary and alternative medicine (CAM) by unaffected women at high risk of breast cancer.

Methods

Self-reported CAM use by women from multiple-case breast cancer families was obtained by questionnaire. Factors associated with CAM use were assessed using multiple logistic regression.

Results

Of 892 women, 55 % (n = 489) used CAM, 6 % (n = 53) specifically to prevent cancer. CAM use was independently associated with tertiary education level (OR 2.56, 95 % CI 1.83–3.58, p < 0.001), greater physical activity (OR 1.05 per hour of physical activity/week, 95 % CI 1.00–1.10, p = 0.049), greater anxiety (OR 1.92, 95 % CI 1.16–3.16, p = 0.01), not currently smoking (OR 0.64, 95 % CI 0.42–0.97, p = 0.037) and lower perceived BC risk (OR 0.82 per 20 percentage points, 95 % CI 0.72–0.94, p = 0.005).

Conclusions

The majority of high-risk women use CAM, but mostly for reasons other than cancer prevention. Most predictors of CAM use are consistent with the limited literature for women at high risk for cancer.