S. aureus procures heme-iron from hemoglobin using tri-domain receptors.
PRE NMR is used to model the 38.8-kDa receptor structure.
Ensemble calculations were used to estimate domain mobility within the receptor.
270">Receptor may trigger heme release from human hemoglobin by perturbing its F helix.
275">This study reveals how Gram-positive bacteria acquire iron from human hemoglobin.