Clinical predictors of early acute respiratory distress syndrome in trauma patients

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• 作者：Michael P. O'Leary ; M.D. ; Jessica A. Keeley ; M.D. ; Arthur Yule ; B.S. ; Caitlyn Suruki ; B.S. ; David S. Plurad ; M.D. ; Ashkan Moazzez ; M.D. ; M.P.H. ; Angela L. Neville ; M.D. ; Brant A. Putnam ; M.D. ; Dennis Y. Kim ; M.D. ; ^{dekim@dhs.lacounty.gov}
• 关键词：Acute respiratory distress syndrome ; Trauma ; Predictors
• 刊名：The American Journal of Surgery
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：212
• 期：6
• 页码：1096-1100
• 全文大小：153 K
• 卷排序：212

文摘

The objectives of this study were to examine the incidence and severity of early acute respiratory distress syndrome (ARDS) according to the Berlin Definition and to identify risk factors associated with the development of early post-traumatic ARDS.MethodsA 2.5-year retrospective database of adult trauma patients who required mechanical ventilation for greater than 48 hours at a level 1 trauma center was analyzed for variables predictive of early (<48 hours after injury), mild, moderate, and severe ARDS and in-hospital mortality.ResultsOf 305 patients, 59 (19.3%) developed early ARDS: mild, 27 (45.8%); moderate, 26 (44.1%); and severe, 6 (10.1%). Performance of an emergent thoracotomy, blunt mechanism, and fresh frozen plasma administration were independently associated with the development of early ARDS. ARDS was not predictive of mortality.ConclusionsTrauma patients with blunt mechanism, who receive fresh frozen plasma, or undergo thoracotomy, are at risk of developing early ARDS.