Dysvascular lower extremity amputations are most commonly associated with diabetes mellitus (DM) and peripheral artery disease (PAD).
Synergistic effect of DM and PAD on postoperative outcomes has not been clarified.
We investigated postoperative 30-day outcomes using Japanese inpatient database.
Postoperative mortality did not differ between patients with DM, PAD, and both.
Patients with both DM and PAD were more likely to have postoperative cardiac events.