Graphene oxide-gold nanoparticles hybrids-based surface plasmon resonance for sensitive detection of microRNA
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- 作者：Qing Wang ; Qing Li ; Xiaohai Yang ; Kemin Wang ; kmwang@hnu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Shasha Du ; Hua Zhang ; Yajie Nie
- 关键词：Surface plasmon resonance ; MicroRNA ; Graphene oxide&ndash ; gold nanoparticles hybrids
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：1001-1007
- 全文大小：1886 K
文摘
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A simple SPR biosensor for sensitive and selective detection of miRNA was introduced.
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The GO–AuNPs hybrids were used as signal tags to enhance the SPR signal.
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It can be used for miRNA detection in cancer cell extractions.
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This assay has great promise for biomedical research and early clinical diagnostics.