An efficient fluorination of β-ketosulfones promoted by a room-temperature ionic liquid at ambient conditions under ultrasound irradiation using Selectfluor™ F-TEDA-BF₄

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• 作者：Mohammad Reza Poor Heravi
• 关键词：Fluorination ; Ultrasound irradiation ; β ; -Ketosulfones ; Selectfluor™ ; Ionic liquids (ILs)
• 刊名：Chinese Chemical Letters
• 出版年：2010
• 出版时间：December 2010
• 年：2010
• 卷：21
• 期：12
• 页码：1399-1402
• 全文大小：142 K

文摘

The fluorination reaction involving a β-ketosulfones by Selectfluor™ was efficiently promoted by the ionic liquid, [Hbim]BF₄ (IL) as a reaction medium with methanol as co-solvent at room temperature under ultrasonic irradiation to afford the corresponding mono and difluoro-β-ketosulfones in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under room temperature without the requirement of any added catalyst under ultrasonic irradiation.