Mechanical-chemical analyses and sub-chronic systemic toxicity of chemical treated organic bovine bone
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- 作者：Kwang-il Lee ; jasonklee77@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jung-soo Lee ; Keun-soo Lee ; Hong-hee Jung ; Chan-min Ahn ; Young-sik Kim ; Young-bock Shim ; Ju-woong Jang ; orienta@empal.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bone graft ; Bovine bone ; Bending strength ; Sub-chronic ; Toxicity ; Xenograft
- 刊名：Regulatory Toxicology and Pharmacology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：73
- 期：3
- 页码：747-753
- 全文大小：938 K
文摘
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The chemical treated bovine bone had significantly higher bending strength than the heat treated bone.
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The chemical appearance of all the materials was same such as 100% hydroxyapatite and Ca/P ratio.
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There was no significant sub-chronic toxicity of chemical treated bone in the rat muscle during 12 weeks.