9- and 13-Hydroxy-octadecadienoic acids (9 + 13 HODE) are inversely related to granulocyte colony stimulating factor and IL-6 in runners after 2 h running
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- 作者：David C. Niemana ; niemandc@appstate.edu" class="auth_mail" title="E-mail the corresponding author ; Mary Pat Meaneya ; Casey S. Johna ; Kevin J. Knaggeb ; Huiyuan Chenb
- 关键词：Running ; Cytokines ; Inflammation ; Oxidative stress ; Muscle damage ; Soreness
- 刊名：Brain, Behavior, and Immunity
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：56
- 期：Complete
- 页码：246-252
- 全文大小：401 K
文摘
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Oxidized linoleic acid metabolites include 9- and 13-hydroxy-octadecadienoic acid (9 + 13 HODE).
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HODES are both a stable indicator of oxidative stress and a strong regulator of inflammation.
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This study explored linkages between 9 + 13 HODE, CRP, muscle damage/soreness, and six cytokines.
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1.5-h running and 30 min downhill running induced a 3.1-fold increase in plasma 9 + 13 HODE.
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A negative relationship between post-exercise 9 + 13 HODE and GCSF and IL-6 was measured.