- 作者：Khairul Majumdera ; b ; khairul.majumder@karolinska.se" class="auth_mail" title="E-mail the corresponding author ; Sten Nilssona ; Hemming Johanssonb ; Anders Ullé ; na ; b ; Bo Lennernä ; sd ; Mia Bergenmara ; c ; Yvonne Brandberga
- 关键词：Prostate cancer ; Anti-androgen ; Sexual function ; Radiation therapy
- 刊名：European Journal of Cancer
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：65
- 期：Complete
- 页码：43-51
- 全文大小：472 K
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Randomised Controlled Trial to study differences in health-related quality of life in curative intended prostate cancer patients after randomising androgen receptor inhibitor monotherapy versus castration plus an androgen receptor inhibitor.
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Mainly intermediate-risk group of prostate cancer patients were included at Radiumhemmet, Karolinska Univeristy Hospital, Sweden with a ratio of 1:1.
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Two European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaires were used (EORTC QLQ C-30 + EORTC QLQ PR25).
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Better sexual interset was noted in patients treated with androgen receptor inhibitor monotherapy compared to castration plus an androgen receptor inhibitor at 3 and 18-month follow-up assessments.
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Study was not powered enough to address on overall survival due to relatively small sample size and shorter follow-up time.