Flaxseed extract exhibits mucosal protective effect in acetic acid induced colitis in mice by modulating cytokines, antioxidant and antiinflammatory mechanisms
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- 作者：Amber Hanif Pallaa ; Najeeha Talat Iqbala ; b ; Khurram Minhasc ; Anwarul-Hassan Gilania ; d ; anwar.gilani@aku.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ulcerative colitis ; Innate immune arm ; IL-17 ; IFN-gamma ; Goblet cells ; Natural products
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：38
- 期：Complete
- 页码：153-166
- 全文大小：2581 K
文摘
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Flaxseed extract reduces IFN-γ and TNF-α in acetic acid induced colitis in mice.
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Flaxseed extract increases IL-17 levels in acetic acid induced colitis in mice.
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Flaxseed extract reduces the malondialdehyde activity in acetic acid colitic mice.
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Flaxseed extract reduces the myeloperoxidase activity in acetic acid colitic mice.
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Flaxseed extract increases the antioxidant activity in acetic acid colitic mice.
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Flaxseed extract retains mucin secreting goblet cells in acetic acid colitic mice.