Stereoselective synthesis of benzosulfamidate-fused tetrahydroquinazoline scaffold via organocatalytic [4+2] cycloaddition of 2-amino-β-nitrostyrenses of cyclic N-sulfimines

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• 作者：Jong-Tack Sim ; Hanna Kim ; Sung-Gon Kim ; ^{sgkim123@kyonggi.ac.kr}
• 关键词：Benzosulfamidate ; Quinazoline ; Cycloaddition reaction ; Michael reaction ; Organocatalyst
• 刊名：Tetrahedron Letters
• 出版年：2016
• 出版时间：28 December 2016
• 年：2016
• 卷：57
• 期：52
• 页码：5907-5910
• 全文大小：722 K
• 卷排序：57

文摘

Concise synthesis of benzosulfamidate-fused tetrahydroquinazolines is developed. The method involves [4+2] cycloaddition reaction of o-N-Cbz-amino-β-nitrostyrene. Asymmetric [4+2] cycloaddition reaction is achieved.