Glycerol acts as alternative electron sink during syngas fermentation by thermophilic anaerobe Moorella thermoacetica

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• 作者：Zen-ichiro Kimura¹ ; Akihisa Kita² ; Yuki Iwasaki² ; Yutaka Nakashimada² ; Tamotsu Hoshino¹ ; Katsuji Murakami¹ ; ^{katsuji-murakami@aist.go.jp" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Anaerobe ; Electron sink ; Glycerol ; Moorella thermoacetica ; Syngas ; Thermophilic
• 刊名：Journal of Bioscience and Bioengineering
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：121
• 期：3
• 页码：268-273
• 全文大小：1121 K

文摘

Moorella thermoacetica is an anaerobic thermophilic acetogen that is capable of fermenting sugars, H₂/CO₂ and syngas (H₂/CO). For this reason, this bacterium is potentially useful for biotechnology applications, particularly the production of biofuel from CO₂. A soil isolate of M. thermoacetica, strain Y72, produces both ethanol and acetate from H₂/CO₂; however, the maximum concentrations of these two products are too low to enable commercialization of the syngas fermentation process. In the present study, glycerol was identified as a novel electron sink among the fermentation products of strain Y72. Notably, a 1.5-fold increase in the production of ethanol (1.4 mM) was observed in cultures supplemented with glycerol during syngas fermentation. This discovery is expected to aid in the development of novel methods that allow for the regulation of metabolic pathways to direct and increase the production of desirable fermentative compounds.