Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test

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• 作者：A.H.L. Bruning¹ ; ^{a.h.bruning@amc.uva.nl" class="auth_mail" title="E-mail the corresponding author} ; P. Susi² ; H. Toivola³ ; A. Christensen⁴ ; M. Sö ; derlund-Venermo⁵ ; K. Hedman⁵ ; H. Aatola³ ; A. Zvirbliene⁶ ; J.O. Koskinen³
• 关键词：Human bocavirus ; human bocavirus 1 ; point-of-care test ; rapid antigen detection assay ; respiratory infection
• 刊名：New Microbes and New Infections
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：11
• 期：Complete
• 页码：17-19
• 全文大小：124 K

文摘

Clinically relevant diagnosis of human bocavirus 1 (HBoV1) is challenging, as the virus is frequently detected in asymptomatic patients, and cofindings with other respiratory viruses are common. The clinical value of current diagnostic methods, such as PCR, is therefore low, and alternative diagnostic strategies are needed. We describe for the first time the use of an antigen detection assay for the rapid identification of HBoV1 in a paediatric patient with respiratory tract infection symptoms. We estimate the duration of active HBoV1 infection to be 6 days.