Antineutrophil Cytoplasmic Antibody—Associated Multiple Giant Saccular Aortic Aneurysms

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• 作者：Ryoji Kinoshita ; MD ; Tomohiro Mizuno ; MD ; PhD ; ^{t-mizuno@yhc.att.ne.jp} ; Tsuyoshi Hachimaru ; MD ; Keiji Oi ; MD ; PhD ; Masafumi Yashima ; MD ; Eiki Nagaoka ; MD ; PhD ; Tatsuki Fujiwara ; MD ; Hidehito Kuroki ; MD ; Dai Tasaki ; MD ; Hirokuni Arai ; MD ; PhD
• 刊名：The Annals of Thoracic Surgery
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：103
• 期：2
• 页码：e153-e155
• 全文大小：1381 K
• 卷排序：103

文摘

We describe a very rare case of a 67-year-old man with multiple saccular aortic aneurysms throughout the entire aorta due to antineutrophil cytoplasmic antibody—associated vasculitis (AAV). The patient underwent staged aortic surgical procedures, including stent-graft insertion for a left iliac artery aneurysm, thoracic endovascular aortic repair for a descending aortic aneurysm, and total replacement of the ascending aorta and aortic arch with the use of high-dose steroids to control inflammation. The histologic findings demonstrated that the damage to the vasa vasorum of the adventitia resulting from AAV caused ischemia of the media, resulting in the formation of saccular aneurysmal changes.