We conducted a prospective cohort study of 38,214 public sector employees with no record of diagnosed depression. Optimism and pessimism were measured using the Revised Life Orientation Test (LOT-R). Records of long-term (> 90 days) work disability with a diagnosis of depression and subsequent return to work until the end of 2005 were obtained from the national health registers.
During the mean follow-up of 4.0 (SD = 2.3) years, 287 employees encountered work disability with a diagnosis of depression. Of them, 164 (57 % ) returned to work during the follow-up. One unit increase in the optimism mean score (range 1–4) was associated with a 25 % lower risk of work disability due to depression and a 37 % higher probability of returning to work after a work disability period when adjusted for age and sex. In the fully-adjusted model hazard ratios per one unit increase in optimism were 0.79 (95 % CI 0.66–0.96) for work disability and 1.30 (95 % CI 1.01–1.66) for return to work. The pessimism mean score (range 1–4) was only associated with a lower probability of returning to work (fully-adjusted HR per one unit increase 0.66, 95 % Cl 0.49–0.88).
The level of optimism was a stronger predictor of work disability with a diagnosis of depression than the level of pessimism, while both optimism and pessimism predicted returning to work.