Cadmium exposure as measured in blood in relation to macrophage density in symptomatic atherosclerotic plaques from human carotid artery
详细信息 查看全文
- 作者：Bjö ; rn Fagerberga ; bjorn.fagerberg@wlab.gu.se" class="auth_mail" title="E-mail the corresponding author ; Josefin Kjelldahla ; josefin.kjelldahl@wlab.gu.se" class="auth_mail" title="E-mail the corresponding author ; Gerd Sallstenb ; gerd.sallsten@amm.gu.se" class="auth_mail" title="E-mail the corresponding author ; Lars Barregardb ; lars.barregard@amm.gu.se" class="auth_mail" title="E-mail the corresponding author ; Niklas Forsgardc ; niklas.forsgard@vgregion.se" class="auth_mail" title="E-mail the corresponding author ; Klas Ö ; sterberga ; klas.osterberg@vgregion.se" class="auth_mail" title="E-mail the corresponding author ; Lillemor Mattsson Hulté ; na ; c ; lillemor.mattsson@wlab.gu.se" class="auth_mail" title="E-mail the corresponding author ; Gö ; ran Bergströ ; ma ; goran.bergstrom@hjl.gu.se" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cadmium ; Carotid artery ; Cardiovascular disease ; Atherosclerosis ; Plaque ; Macrophage ; Inflammation
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：249
- 期：Complete
- 页码：209-214
- 全文大小：485 K
文摘
- bel">•
Symptomatic carotid plaques most often rupture close to the bifurcation.
- bel">•
Blood cadmium is associated with CD68 stained areas close to the bifurcation.
- bel">•
Cadmium is unrelated to CD14 stained areas as a measure of macrophage activation.
- bel">•
Cadmium exposure is associated with accumulation of pro-inflammatory macrophages.
- bel">•
These data add to current knowledge of the pro-atherogenic effect of cadmium.