In vitro selection of peptide aptamers using a ribosome display for a conducting polymer

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• 作者：Zha Li¹ ; ² ; ³ ; Takanori Uzawa¹ ; ² ; Haichao Zhao⁴ ; Shyh-Chyang Luo⁴ ; Hsiao-hua Yu⁴ ; Eiry Kobatake³ ; Yoshihiro Ito¹ ; ² ; ³ ; ^{y-ito@riken.jp" class="auth_mail} ; ^{yito7335@gmail.com" class="auth_mail}
• 关键词：In vitro selection ; Ribosome display ; Poly(3-hexylthiophene-2 ; 5-diyl) ; Peptide aptamer ; Binding ability
• 刊名：Journal of Bioscience and Bioengineering
• 出版年：April, 2014
• 年：2014
• 卷：117
• 期：4
• 页码：501-503
• 全文大小：307 K

文摘

Ribosome display was used to select peptide aptamers from a random library composed of hydrophilic amino acids for a conducting polymer, poly(3-hexylthiophene-2,5-diyl). Binding of aptamers was measured by quartz crystal microbalance, and the secondary structure of the peptide was investigated by circular dichroism.