Associations among circulating branched-chain amino acids and tyrosine with muscle volume and glucose metabolism in individuals without diabetes
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- 作者：Tatsuro Honda ; M.S.a ; b ; c ; Yoshinao Kobayashi ; M.D. ; Ph.D.b ; c ; yoshinao@hac.mie-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Kenji Togashi ; Ph.D.d ; Hiroshi Hasegawa ; M.D. ; Ph.D.b ; Motoh Iwasa ; M.D. ; Ph.D.b ; Osamu Taguchi ; M.D. ; Ph.D.c ; Yoshiyuki Takei ; M.D. ; Ph.D.b ; Yasuhiro Sumida ; M.D. ; Ph.D.c ; e
- 关键词：Insulin resistance ; β-cell function ; Fasting blood glucose ; Spearman's test ; Stepwise multiple regression analysis
- 刊名：Nutrition
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：32
- 期：5
- 页码：531-538
- 全文大小：662 K
文摘
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Branched-chain amino acids (BCAA) positively associated with insulin sensitivity in individuals without diabetes.
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Muscle volume was important for circulating levels of BCAA and tyrosine (Tyr).
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BCAA correlated with increased fasting blood glucose and fasting immunoreactive insulin (IRI) levels.
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Serum BCAA and Tyr levels were higher in men than in women.
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Tyr did not affect insulin sensitivity but was associated with fasting IRI levels.