Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling
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- 作者：Takuya Matsumoto1 ; 2 ; 13 ; Koki Fujimori1 ; 13 ; Tomoko Andoh-Noda1 ; 3 ; Takayuki Ando1 ; Naoko Kuzumaki1 ; 4 ; Manabu Toyoshima5 ; Hirobumi Tada6 ; Kent Imaizumi1 ; Mitsuru Ishikawa1 ; Ryo Yamaguchi1 ; 7 ; Miho Isoda1 ; 7 ; Zhi Zhou1 ; Shigeto Sato8 ; Tetsuro Kobayashi9 ; Manami Ohtaka10 ; Ken Nishimura10 ; 11 ; Hiroshi Kurosawa3 ; Takeo Yoshikawa5 ; Takuya Takahashi6 ; Mahito Nakanishi10 ; Manabu Ohyama9 ; 14 ; Nobutaka Hattori8 ; Wado Akamatsu1 ; 12 ; awado@juntendo.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hideyuki Okano1 ; hidokano@a2.keio.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Stem Cell Reports
- 出版年：2016
- 出版时间：8 March 2016
- 年：2016
- 卷：6
- 期：3
- 页码：422-435
- 全文大小：3342 K
文摘
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TiPSCs are a suitable source for neural disease modeling
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Developing a robust neurosphere-based induction protocol
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An optimized differentiation protocol can overcome clonal variations
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Modeling Parkinson's disease using TiPSC-derived neurons