Effects of Fluvastatin on Plasma Levels of Low-Density Lipoprotein Subfractions, Oxidized Low-Density Lipoprotein, and Soluble Adhesion Molecules: A Twenty-Four–Week, Open-Label, Dose-Increasing
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- 作者：Homma ; Yasuhiko ; Homma ; Koichiro ; Iizuka ; Shinichi ; Iigaya ; Kamon
- 关键词：fluvastatin ; lipoprotein subfractions ; oxidized LDL ; adhesion molecules ; reverse cholesterol transport ; carotid arteriosclerosis
- 刊名：Current Therapeutic Research
- 出版年：2003
- 出版时间：April, 2003
- 年：2003
- 卷：64
- 期：4
- 页码：236-247
- 全文大小：99.6 K
文摘
Background: Statins not only lower low-density lipoprotein (LDL) levels, but also have several antiarteriosclerotic effects (eg, decreasing arterial inflammation and arterial smooth muscle cell proliferation, as well as antioxidant effects). The relationship between the dose of statin and its effects on plasma LDL levels and other arteriosclerosis-related effects remains to be clarified.