Systemic administration of vitamins C and E attenuates nociception induced by chronic constriction injury of the sciatic nerve in rats
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- 作者：Ana Paula K. Riffel ; anapkr@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jé ; ssica A. de Souza ; Maria do Carmo Q. Santos ; André ; a Horst ; Taí ; na Scheid ; Carolina Kolberg ; Adriane Belló ; -Klein ; Wania A. Partata
- 关键词：Mechanical threshold ; Thermal threshold ; Sciatic functional index ; Antioxidant ; Lipid peroxidation ; Oxidative stress
- 刊名：Brain Research Bulletin
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：169-177
- 全文大小：1965 K
文摘
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Vitamin C and E increase thermal and mechanical thresholds in CCI rats.
Antinociceptive effect of vitamin C and E and vitamin C + E in CCI rats.
Vitamin C and E and vitamin C + E ameliorate sciatic functional index in CCI rats.
Highest antinociception with co-administration of vitamin C + E and gabapentin.