Herd immunity after two years of the universal mass vaccination program against rotavirus gastroenteritis in Austria

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• 作者：Maria Paulke-Korinek^a ; Michael Kundi^b ; Pamela Rendi-Wagner^c ; Alfred de Martin^d ; Gerald Eder^e ; Birgit Schmidle-Loss^a ; Andreas Vecsei^f ; Herwig Kollaritsch^a ; ^e ; ^{herwig.kollaritsch@meduniwien.ac.at}
• 关键词：Rotavirus gastroenteritis ; Mass vaccination program ; Herd effect
• 刊名：Vaccine
• 出版年：2011
• 出版时间：24 March 2011
• 年：2011
• 卷：29
• 期：15
• 页码：2791-2796
• 全文大小：265 K

文摘

Austria was the first country in Europe implementing a universal mass vaccination program against rotavirus gastroenteritis (RV-GE) for all infants nationwide. Epidemiological data from a hospital based surveillance system show that incidence rates of children hospitalized with RV-GE decreased in 2009 compared to 2008 and compared to the prevaccination period 2001–2005. Decreasing hospitalization-rates from RV-GE were observed in children of all age groups, even in those not eligible for vaccination according to their age, suggesting herd immunity induced by universal mass vaccination against RV-GE. In 2009 the disease burden was highest in children below three months of age stressing the importance of the early start of the immunization course.