Assessment of Mitral Annulus Size and Function by Real-time 3-Dimensional Echocardiography in Cardiomyopathy: Comparison with Magnetic Resonance Imaging

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• 作者：Ashraf M. Anwar ; MD^&dagger ; ; Osama I.I. Soliman ; MD^&dagger ; ; Attila Nemes ; MD ; PhD^§ ; ; Tjeerd Germans ; MD^&Dagger ; ; Boudewijn J. Krenning ; MD^?/sup> ; Marcel L. Geleijnse ; MD ; PhD^?/sup> ; Albert C. Van Rossum ; MD^&Dagger ; ; Folkert J. ten Cate ; MD ; PhD^?/sup> ; ^{f.j.tencate@erasmusmc.nl}
• 刊名：Journal of the American Society of Echocardiography
• 出版年：2007
• 出版时间：August 2007
• 年：2007
• 卷：20
• 期：8
• 页码：941-948
• 全文大小：330 K

文摘

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Objective

We sought to assess mitral annular (MA) size and function in hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) using real-time 3-dimensional (3D) echocardiography (RT3DE).

Methods

The study included 30 patients with HCM, 20 patients with DCM, and 30 control subjects. RT3DE measurements included end-systolic and end-diastolic MA area (MAA) (MAA_3D), MA diameter_3D, MA fractional area change (MAFAC), and MA fractional shortening. In subgroup of 50 patients, magnetic resonance imaging (MRI) was used for MAA_MRI and MA diameter_MRI measurement.

Results

End-diastolic MAA_3D was larger in HCM than in control group (P < .0001). Higher MAFAC and MA fractional shortening were present in HCM than in control group (P = .001 and P = .006, respectively). End-systolic and end-diastolic MAA_3D in DCM were higher than in HCM and control groups (P < .0001). Lower MAFAC and MA fractional shortening were present in DCM than in HCM and control groups (P < .0001). MAFAC correlated well with left ventricular function in control subjects (r = 0.94, P < .0001), whereas correlation was less in DCM (r = 0.53, P = .02) and HCM (r = 0.42, P < .01). RT3DE and MRI measurements were comparable.

Conclusion

RT3DE assessment of MA size and function in control subjects and patients with cardiomyopathy is accurate and well correlated with MRI.