Biomaterial-based regional chemotherapy: Local anticancer drug delivery to enhance chemotherapy and minimize its side-effects
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- 作者：Katarzyna Krukiewicz ; katarzyna.krukiewicz@polsl.pl" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Jerzy K. Zak jerzy.zak@polsl.pl" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Regional chemotherapy ; Local drug delivery ; Anticancer implants ; Drug carriers ; Biomaterials
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 May 2016
- 年：2016
- 卷：62
- 期：Complete
- 页码：927-942
- 全文大小：625 K
文摘
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Regional chemotherapy is used to enhance therapeutic efficiency of anticancer drugs.
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Local delivery of anticancer drugs reduces their toxic effects to healthy tissues.
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This review summarizes different approaches of local delivery of chemotherapeutics.
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The wide range of biomaterials used as reservoirs of anticancer drugs is described.
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Commercially available products approved by relevant health agencies are presented.