The genetic profile of susceptibility to infectious diseases in Roman-Period populations from Central Poland

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• 作者：Magda Lewandowska ; ^{magda.lewandowska@stud.umed.lodz.pl} ; Krystyna Jędrychowska-Dańska ; Alicja Zamerska ; Tomasz Płoszaj ; Henryk W. Witas
• 关键词：Ancient DNA ; Natural selection ; Genetic drift ; Innate immune response
• 刊名：Infection, Genetics and Evolution
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：47
• 期：Complete
• 页码：1-8
• 全文大小：381 K
• 卷排序：47

文摘

Genetic profile of innate immune response in ancient Polish groups was assessed. Alleles frequency is moderately similar in ancient and modern populations. Genetic drift, inbreeding and reduced gene flow drove changes in allele frequencies.