Early life exposure to PCB126 results in delayed mortality and growth impairment in the zebrafish larvae
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- 作者：Carolina Di Paoloa ; b ; 1 ; carolina.dipaolo@bio5.rwth-aachen.de" class="auth_mail" title="E-mail the corresponding author ; Ksenia J. Grohc ; d ; 1 ; ksenia.groh@eawag.ch" class="auth_mail" title="E-mail the corresponding author ; Markus Zennegge ; markus.zennegg@empa.ch" class="auth_mail" title="E-mail the corresponding author ; Etië ; nne L.M. Vermeirssena ; etienne.vermeirssen@oekotoxzentrum.ch" class="auth_mail" title="E-mail the corresponding author ; Albertinka J. Murkf ; g ; tinka.murk@wur.nl" class="auth_mail" title="E-mail the corresponding author ; Rik I.L. Eggenc ; h ; rik.eggen@eawag.ch" class="auth_mail" title="E-mail the corresponding author ; Henner Hollertb ; henner.hollert@bio5.rwth-aachen.de" class="auth_mail" title="E-mail the corresponding author ; Inge Wernera ; inge.werner@oekotoxzentrum.ch" class="auth_mail" title="E-mail the corresponding author ; Kristin Schirmerc ; h ; i ; kristin.schirmer@eawag.ch" class="auth_mail" title="E-mail the corresponding author
- 关键词：Zebrafish ; Early life stages ; Delayed effects ; Sublethal effects ; Growth ; PCB126
- 刊名：Aquatic Toxicology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：169
- 期：Complete
- 页码：168-178
- 全文大小：1294 K
文摘
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PCB126 residues did not reach steady state within the five days of exposure.
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Early life exposure to PCB126 impaired metamorphosis and growth in zebrafish larvae.
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Critical periods for PCB toxicity in larval development were identified.
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Temporal profiles of delayed toxicity were comparable between zebrafish and sole.
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Effects on swim bladder and skeleton are promising for delayed toxicity prediction.