Malignant myoepithelioma of the soft palate

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• 作者：Irving J. Mej&iacute ; a-Herná ; ndez^a ; Ana Ma. Cano Valdez^b ; ^c ; Denise De Leó ; n-Trenado^b ; Kuauhyama Luna-Ort&iacute ; z^a ; ^c ; ^{kuauhyama@yahoo.com.mx} ; ^{kuauhyama@starmedia.com}
• 关键词：Malignant myoepithelioma ; Soft palate ; Pleomorphic adenoma ; Carcinoma
• 刊名：Auris Nasus Larynx
• 出版年：2013
• 出版时间：April, 2013
• 年：2013
• 卷：40
• 期：2
• 页码：231-234
• 全文大小：1046 K

文摘

Malignant myoepitheliomas (MM) (myoepithelial carcinomas) are rare tumors representing <1 % of salivary gland tumors. They are characterized as being locally aggressive. Rarely do they present distant metastases; however, when they do metastasize the sites most affected are the lungs, liver, pleura, peritoneum and skin. They may originate de novo in a pleomorphic adenoma or a benign myoepithelioma. We report the case of a patient with a submucosal lesion of the soft palate measuring ¡«4 cm ¡Á 3 cm. The patient underwent transoral resection with a microscope and CO₂ laser. Histopathological report was MM originating in a pleomorphic adenoma. Management of this neoplasm is controversial. Myoepithelial carcinoma is a rare neoplasm whose diagnosis includes immunohistochemical (IHC) studies. Surgery is the cornerstone of treatment. Management with laser surgery may preserve the function of the soft palate without deterioration of the quality of life in these patients.