Adiponectin Enhances Antibacterial Activity of Hematopoietic Cells by Suppressing Bone Marrow Inflammation
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- 作者：Yosuke Masamoto1 ; 2 ; Shunya Arai1 ; Tomohiko Sato1 ; 2 ; Akihide Yoshimi1 ; Naoto Kubota3 ; Iseki Takamoto3 ; Yoichiro Iwakura4 ; Akihiko Yoshimura5 ; Takashi Kadowaki3 ; Mineo Kurokawa1 ; kurokawa-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Immunity
- 出版年：2016
- 出版时间：21 June 2016
- 年：2016
- 卷：44
- 期：6
- 页码：1422-1433
- 全文大小：2125 K
文摘
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Diet-induced obesity impairs granulopoiesis and bacterial clearance upon infection
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Obesity induces inflammation in the bone marrow through adiponectin deficiency
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Excessive TNF inhibits demand-driven expansion of hematopoietic progenitor cells
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Exogenous adiponectin can be therapeutic in obesity-associated infections in mice