A Novel Diagnostic and Prognostic Biomarker Panel for Endothelial Cell Damage-Related Complications in Allogeneic Transplantation
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- 作者：Shotaro Tatekawa1 ; 2 ; Akio Kohno2 ; Kazutaka Ozeki2 ; Koichi Watamoto2 ; 3 ; Norihiro Ueda2 ; 4 ; Yohei Yamaguchi2 ; 5 ; Tsutomu Kobayashi1 ; Isao Yokota6 ; Satoshi Teramukai6 ; Masafumi Taniwaki1 ; Junya Kuroda1 ; junkuro@koto.kpu-m.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Yoshihisa Morishita2 ; 7
- 关键词：Transplantation-related complications ; Endothelial cell damage ; Sinusoidal occlusive syndrome ; Transplantation-associated microangiopathy ; Biomarkers ; Angiopoietin 2 ; Allogeneic hematopoietic stem cell transplantation
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：22
- 期：9
- 页码：1573-1581
- 全文大小：1266 K
文摘
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Four biomarkers, including angiopoietin 2, are associated with transplantation-related complications with endothelial cell damage
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The composite panel including these biomarkers had diagnostic and prognostic values for transplantation-related complications with endothelial cell damage
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The composite panel also predicted overall survival and nonrelapse mortality of patients with transplantation-related complications with endothelial cell damage