Transcriptome analysis of Lactococcus lactis subsp. lactis during milk acidification as affected by dissolved oxygen and the redox potential
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- 作者：Nadja Larsena ; nf@food.ku.dk" class="auth_mail" title="E-mail the corresponding author ; Saloomeh Moslehi-Jenabiana ; Birgit Brø ; sted Wernera ; Maiken Lund Jensenb ; Christel Garriguesb ; Finn Kvist Vogensena ; Lene Jespersena
- 关键词：Lactococcus lactis ; Milk acidification ; Transcriptome analysis ; Dissolved oxygen ; Redox potential
- 刊名：International Journal of Food Microbiology
- 出版年：2016
- 出版时间：2 June 2016
- 年：2016
- 卷：226
- 期：Complete
- 页码：5-12
- 全文大小：438 K
文摘
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Initial levels of oxygen had an impact on gene expression of Lactococcus lactis ssp. lactis during milk acidification.
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Genes involved in trehalose and purine nucleotide biosynthesis were affected by oxidative stress.
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Genes up-regulated in response to oxygen depletion were involved in pyrimidine, arginine and branched amino acids pathways.
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Genes involved in salvage nucleotide biosynthesis and cysteine pathways were repressed after oxygen depletion.
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Shifts in expression of pyruvate metabolic genes towards mixed acid fermentation after oxygen depletion.