Visual hallucinations (VH) have been linked to cholinergic dysfunction and mono-amine imbalance.
Apomorphine is well tolerated in advanced PD patients in contrast to other dopamine agonists.
Anecdotal evidence even suggests a beneficial effect of apomorphine on VH in PD.
Its positive effect might be related to the action of the piperidine moiety of apomorphine.
Anti-hallucinogenic potential of apomorphine due to serotonin antagonism (5-HT2A) in particular.