A CFD model was developed to predict 尾-lactoglobulin denaturation in a plate heat exchanger.
A k–蔚 turbulence model is well-suited for modeling plate heat exchanger hydrodynamics.
The protein denaturation was measured before and after heat treatment at pilot-scale.
The kinetic parameters provide a close correlation between the CFD model and experiments.
The unfolded 尾-lactoglobulin species is the precursor of fouling in the exchanger.