Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas
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- 作者：Nordsmark ; Marianne ; Loncaster ; Juliette ; Aquino-Parsons ; Christina ; Chou ; Shu-Chuan ; Ladekarl ; Morten ; et. al.
- 关键词：Tumour oxygenation ; Hypoxia marker ; Pimonidazole ; Uterine cervix carcinoma
- 刊名：Radiotherapy and Oncology
- 出版年：2003
- 出版时间：April, 2003
- 年：2003
- 卷：67
- 期：1
- 页码：35-44
- 全文大小：192 K
文摘
Background and purpose: The measurement of tumour oxygenation using Eppendorf oxygen-sensitive needle electrodes can provide prognostic information but the method is limited to accessible tumours that are suitable for electrode insertion. In this paper the aim was to study the relationship between such physiological measurements of tumour hypoxia and the labelling of tumours with the hypoxia-specific marker pimonidazole.