Prospective Evaluation of Ultrasound Accuracy in the Detection of Pelvic Carcinomatosis in Patients with Ovarian Cancer

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• 作者：Vit Weinberger^&lowast ; ; Daniela Fischerova^&dagger ; ; Ivana Semeradova^&dagger ; ; Jiri Slama^&dagger ; ; Pavel Dundr^&Dagger ; ; Ladislav Dusek^§ ; ; David Cibula^&dagger ; ; Michal Zikan^&dagger ; ; ^{michal.zikan@lf1.cuni.cz" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Diagnosis ; Ovarian cancer ; Carcinomatosis ; Peritoneum ; Prospective studies ; Ultrasonography
• 刊名：Ultrasound in Medicine & Biology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：42
• 期：9
• 页码：2196-2202
• 全文大小：769 K

文摘

We analyzed the accuracy of transvaginal sonography in detection of pelvic carcinomatosis in ovarian cancer patients and factors (age, body mass index, performance status, ascites, stage, histotype, tumor grade) influencing the performance of ultrasound. In this prospective study, all 191 consecutively included patients underwent a pre-operative ultrasound staging examination according to institutional protocol. Peritoneal spread was assessed on the basis of peri-operative findings or histology. The area under the receiver operating characteristic curve for the detection of carcinomatosis was 0.90 (0.84–0.93); the sensitivity was 84% (95% confidence interval [CI]: 75%–%90), specificity 96% (95% CI: 89%–99%), positive predictive value 96% (95% CI: 89%–99%), negative predictive value 83% (95% CI: 74%–90%) and overall accuracy 89% (95% CI: 84%–93%). We report that transvaginal sonography is clinically useful in the detection of pelvic carcinomatosis.