The interaction and binding of flavonoids to human serum albumin modify its conformation, stability and resistance against aggregation and oxidative injuries
刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2017
出版时间:January 2017
年:2017
卷:1861
期:1
页码:3531-3539
全文大小:1115 K
卷排序:1861
文摘
Phloretin–HSA complex formation involves property changes in both compounds. Phloretin binds to protein in subdomain IIA. Phloretin modifies the secondary structure of HSA Phloretin–HSA complex is able to withstand degradation due to HCLO and fibrillation.