Congenital High Airway Obstruction Syndrome (CHAOS): A perinatal autopsy case report

详细信息    查看全文

• 作者：Manasi Gosavi ^{mansi.gosavi@gmail.com} ; Lalit Kumar ; ^{drlkumar@gmail.com} ; Ashwini Ratnakar ^{ashwininov5@gmail.com} ; Hema Bannur ^{drhemabannur@yahoo.co.in}
• 关键词：CHAOS ; Congenital abnormalities ; Airway obstruction ; Ascites ; Autopsy
• 刊名：Pathology - Research and Practice
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：213
• 期：2
• 页码：170-175
• 全文大小：3053 K
• 卷排序：213

文摘

Congenital High Airway Obstruction Syndrome (CHAOS) is a rare anomaly where a partial or complete obstruction of upper airway is seen. As a consequence, the foetus develops enlarged lungs, inverted or flattened diaphragm and ascites. The pathological findings in a case of CHAOS is presented.Case reportA 28-year-old primigravida presented with a history of 5 months of amenorrhoea. Ultrasonography revealed enlarged echogenic lungs, cardiac mid-position, inverted diaphragm, foetal ascites and talipes of left foot. The parents opted for termination of pregnancy. Foetal autopsy revealed a male foetus with ascites and talipes of left foot. Lungs were massively enlarged, diaphragm was flattened. A dome-shaped cricoid cartilage at the subglottic level was seen as the cause of obstruction.ConclusionCHAOS is a rare anomaly. A foetal autopsy can be helpful in establishing the level and nature of the obstruction and in documenting other associated foetal anomalies.