Erh1 stoichiometrically interacts with Mmi1 to form a complex called EMC
EMC engages MTREC and CCR4-NOT to assemble facultative heterochromatin
Ccr4 cooperates with Pir2/ARS2 to trigger RNAi-mediated facultative heterochromatin
Erh1 and CCR4-NOT promote rDNA silencing and the maintenance of rDNA integrity