Synergistic antibiofilm efficacy of various commercial antiseptics, enzymes and EDTA: a study of Pseudomonas aeruginosa and Staphylococcus aureus biofilms
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- 作者：Elodie Lefebvre ; Christophe Vighetto ; Patrick Di Martino ; Vé ; ronique Larreta Garde ; veronique.larreta-garde@u-cergy.fr" class="auth_mail" title="E-mail the corresponding author ; Damien Seyer
- 关键词：Biofilm ; Antiseptic ; Enzyme ; EDTA ; Pseudomonas aeruginosa ; Staphylococcus aureus
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：48
- 期：2
- 页码：181-188
- 全文大小：502 K
文摘
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Synergy of various compounds to degrade dense bacterial biofilms.
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First description in the literature of an antimicrobial agent, metal chelator and enzyme combination.
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A 5-log decrease in biofilm bacterial population with low concentration of antiseptics.
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Efficacy of the treatment both against Gram-positive and Gram-negative sessile bacteria in biofilms.