Larvicidal activity of Ramalina usnea lichen against Aedes aegypti

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• 作者：Antô ; nio S.N. Moreira^a ; ^b ; ^{ansernam@iff.edu.br" class="auth_mail" title="E-mail the corresponding author} ; Roberta O.S. Fernandes^c ; Francisco J.A. Lemos^d ; Raimundo Braz-Filho^e ; Ivo J.C. Vieira^e
• 关键词：Larvicidal activity ; Lichenized fungi ; Ramalina usnea ; Aedes aegypti
• 刊名：Revista Brasileira de Farmacognosia
• 出版年：2016
• 出版时间：July-August 2016
• 年：2016
• 卷：26
• 期：4
• 页码：530-532
• 全文大小：313 K

文摘

The larvicidal activity of the methanol extract, fractions and compounds 2-hydroxy-4-methoxy-6-propyl-methyl benzoate and (+)-usnic acid identified from the lichen Ramalina usnea (L.) R. Howe, Ramalinaceae, was tested against the third instar larvae of the Aedes aegypti mosquito. The methanol extract and three fractions showed activity, killing 100% and 96.6% of the larvae at a concentration of 150 μg/ml at 24 h. The isolated compounds, 2-hydroxy-4-methoxy-6-propyl-methyl benzoate and the (+)-usnic acid showed larvicidal activity, presenting LC₅₀ values of 4.85 and 4.48 μg/ml, respectively. This is the first study of its kind reporting the larvicidal activity against the A. aegypti mosquito with compound (1).