Tissue-Resident CD169+ Macrophages Form a Crucial Front Line against Plasmodium Infection
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- 作者：Pravesh Gupta1 ; Si Min Lai1 ; 2 ; Jianpeng Sheng1 ; Piotr Tetlak1 ; Akhila Balachander2 ; Carla Claser2 ; Laurent Renia1 ; 2 ; Klaus Karjalainen1 ; Christiane Ruedl1 ; ruedl@ntu.edu.sg" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：9 August 2016
- 年：2016
- 卷：16
- 期：6
- 页码：1749-1761
- 全文大小：4327 K
文摘
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CD169+ macrophages can control parasite propagation and restrain inflammation
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Lack of CD169+ macrophages augments hemozoin deposition in several organs
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Vascular leakage in CD169-DTR mice occurs during malaria
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Plasmodium infection leads to multi-organ damage in absence of CD169+ macrophages