Long-Term Outcomes after Treatment with Clofarabine ± Fludarabine with Once-Daily Intravenous Busulfan as Pretransplant Conditioning Therapy for Advanced Myeloid Leukemia and Myelodysplastic Syndrome
详细信息 查看全文
- 作者：Gheath Alatrash1 ; Peter F. Thall2 ; Benigno C. Valdez1 ; Patricia S. Fox2 ; Jing Ning2 ; Haven R. Garber1 ; Selma Janbey1 ; Laura L. Worth3 ; Uday Popat1 ; Chitra Hosing1 ; Amin M. Alousi1 ; Partow Kebriaei1 ; Elizabeth J. Shpall1 ; Roy B. Jones1 ; Marcos de Lima1 ; 4 ; Gabriela Rondon1 ; Julianne Chen1 ; Richard E. Champlin1 ; Borje S. Andersson1 ; bandersson@mdanderson.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Conditioning regimen ; Clofarabine ; Busulfan ; Fludarabine ; Allogeneic stem cell transplantation
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：22
- 期：10
- 页码：1792-1800
- 全文大小：1308 K
文摘
- •
Clofarabine is safe when used with i.v. Bu+Flu in pretransplant conditioning regimens.
- •
Pretransplant conditioning with i.v. Bu+Clo+Flu has potent antileukemia activity.
- •
Intravenous Bu+Clo+Flu conditioning is efficacious in patients with aggressive AML/MDS.