Different Respiratory Rates Affect the Measurement of Autonomic Tone by Power Spectral Analysis of Heart Rate Variability in Patients with Heart Failure

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• 作者：John E. S ; erson ; Dickens T. K. Yeung ; Leata Y. C. Yeung ; Richard L. C. Kay ; Brian Tomlinson ; Kam S. Woo ; Luciano Bernardi
• 刊名：Journal of the American College of Cardiology
• 出版年：1995
• 出版时间：February 1995
• 年：1995
• 卷：25
• 期：2, Supplement 1
• 页码：425A
• 全文大小：107 K

文摘

Power spectral analysis of heart rate variability is frequently used as an easy non invasive method for assessing autonomic tone. However changes in respiratory rate are frequently ignored and these may have an important effect on the measurements of spectral components, especially in heart failure. We have assessed the effect of different respiratory rates (10, 15, 20 minp>−1p> and spontaneous) on low frequency (LF) and high frequency (HF) components of HR variability in 11 heart failure pts (CCF) (EF = 40 ± 4 % ; 9 males) and 9 normal subjects (5 males).<p>Results: LF & HF spectral power in normalized units ( % ); S = spontaneous (mean ± SEM)<p>Supine HF power falls with increasing respiratory rate in most CCF pts and this effect is similar to that seen in normals on standing (i.e. at increased sympathetic levels). An improvement in clinical state of CCF pts will lower respiratory rate and this effect alone will increase HF power rather than any therapy.