Higher Early Monocyte and Total Lymphocyte Counts Are Associated with Better Overall Survival after Standard Total Body Irradiation, Cyclophosphamide, and Fludarabine Reduced-Intensity Conditioning Double Umbilical Cord Blood Allogeneic Stem Cell Transplantation in Adults
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- 作者：Amandine Le Bourgeois1 ; amandine.lebourgeois@chu-nantes.fr" class="auth_mail" title="E-mail the corresponding author ; Pierre Peterlin1 ; Thierry Guillaume1 ; Jacques Delaunay1 ; Alix Duquesne2 ; Steven Le Gouill1 ; Philippe Moreau1 ; Mohamad Mohty3 ; Loï ; c Campion4 ; 5 ; Patrice Chevallier1 ; 5
- 关键词：Hematological recovery ; Immune recovery ; Reduced-intensity conditioning regimen ; Double umbilical cord blood ; Allogeneic stem cell transplantation ; Adults
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：22
- 期：8
- 页码：1473-1479
- 全文大小：390 K
文摘
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Higher day +30 monocyte and day +42 lymphocyte counts were independently associated with better overall survival after double umbilical cord blood reduced-intensity conditioning with total body irradiation, cyclophosphamide, and fludarabine allogeneic stem cell transplantation
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These higher counts may confer better graft-versus-disease effect or better protection against infections.