Pre-assembled Nuclear Pores Insert into the Nuclear Envelope during Early Development
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- 作者：Bernhard Hampoelz1 ; Marie-Therese Mackmull1 ; Pedro Machado2 ; Paolo Ronchi2 ; Khanh Huy Bui1 ; 5 ; Nicole Schieber4 ; Rachel Santarella-Mellwig2 ; Aleksandar Necakov1 ; Amparo André ; s-Pons1 ; Jean Marc Philippe3 ; Thomas Lecuit3 ; Yannick Schwab2 ; 4 ; Martin Beck1 ; 4 ; martin.beck@embl.de" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell
- 出版年：2016
- 出版时间：28 July 2016
- 年：2016
- 卷：166
- 期：3
- 页码：664-678
- 全文大小：5703 K
文摘
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Annulate lamellae (AL) NPCs insert into the nuclear envelope during interphase
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AL-NPCs are pore scaffolds devoid of most transport channel nucleoporins
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NE-openings enable AL insertion, yet the permeability barrier remains unperturbed
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AL-NPC insertion operates only before gastrulation