Quantitative Differences in a Single Maternal Factor Determine Survival Probabilities among Drosophila Germ Cells

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• 作者：Maija Slaidina¹ ; Ruth Lehmann¹ ; ² ; ^{ruth.lehmann@med.nyu.edu}
• 关键词：cell-to-cell variability ; quantitative RNA analysis ; germ cells ; Drosophila ; cell fate ; cell death ; wunen ; nanos ; LPP ; lipid phosphate phosphatase ; p53
• 刊名：Current Biology
• 出版年：2017
• 出版时间：23 January 2017
• 年：2017
• 卷：27
• 期：2
• 页码：291-297
• 全文大小：2144 K
• 卷排序：27

文摘

Central and peripheral PGCs inherit different quantities of maternal factors Central cells have higher survival probabilities Lipid phosphate phosphatase Wun2 is a quantitative regulator of PGC survival Wun2 might be used as a readout for germ plasm quantity