We evaluate the sensitivity to L. longipalpis and canine visceral leishmaniasis early detection.

We use the flow analysis, a spatial analysis tool, to identify factors associated with vector dispersal and expansion of visceral leishmaniasis.

The sensitivity for vector and canince visceral leishmaniasis early detection presented reasonable accuracy.

Vector dispersal and expansion of visceral leishmaniasis were from the northwest to the southeast of the state, primarily flanking Marechal Rondon highway.

Vector dispersal and expansion of visceral leishmaniasis in São Paulo State have progressed arithmetically, moving forward at a constant rate from the main cities of microregions.