Auditory cortical change detection in adults with Asperger syndrome

详细信息    查看全文

• 作者：Tuulia Lepistö ; Taina Nieminen-von Wendt ; Lennart von Wendt ; Risto Nä ; ä ; tä ; nen ; Teija Kujala
• 关键词：Asperger syndrome ; Auditory ; Discrimination ; Event-related potentials ; Mismatch negativity (MMN) ; P3a
• 刊名：Neuroscience Letters
• 出版年：2007
• 出版时间：6 March 2007
• 年：2007
• 卷：414
• 期：2
• 页码：136-140
• 全文大小：343 K

文摘

The present study investigated whether auditory deficits reported in children with Asperger syndrome (AS) are also present in adulthood. To this end, event-related potentials (ERPs) were recorded from adults with AS for duration, pitch, and phonetic changes in vowels, and for acoustically matched non-speech stimuli. These subjects had enhanced mismatch negativity (MMN) amplitudes particularly for pitch and duration deviants, indicating enhanced sound-discrimination abilities. Furthermore, as reflected by the P3a, their involuntary orienting was enhanced for changes in non-speech sounds, but tended to be deficient for changes in speech sounds. The results are consistent with those reported earlier in children with AS, except for the duration-MMN, which was diminished in children and enhanced in adults.