Olfactory ensheathing glia cell therapy and tubular conduit enhance nerve regeneration after mouse sciatic nerve transection
详细信息 查看全文
- 作者：Camila Oliveira Goularta ; 1 ; Daniella de Freitas Pereira  ; ngelo Durç ; oa ; 1 ; Lí ; tia Alves de Carvalhob ; Jú ; lia Teixeira Oliveiraa ; Luciné ; ia Alvesb ; Leny A. Cavalcanteb ; leny@biof.ufrj.br" class="auth_mail" title="E-mail the corresponding author ; Ana Maria Blanco Martineza ; b ; anamartinez@hucff.ufrj.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Peripheral nerve trauma ; Nerve regeneration ; Olfactory ; Ensheathing cells ; Nerve conduit ; Cell therapy
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：1650
- 期：Complete
- 页码：243-251
- 全文大小：10220 K
文摘
- •
Associated therapies were tested as strategy to improve nerve regeneration.
- •
Olfactory Ensheathing Cells (OEC) were seeded into a collagen conduit.
- •
Associated therapies improved nerve regeneration morphologically.
- •
OEC transplant also resulted in a better motor function recovery.
- •
OEC therapy can be potentially translated to the clinical set.