Assessment of Indigo (Polygonum tinctorium Ait.) water extracts?bioactive compounds, and their antioxidant and antiproliferative activities

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• 作者：Kyung-su Kim^a ; Won-Gul Hwang^a ; Hong-Gi Jang^b ; Buk-Gu Heo^b ; Milan Suhaj^c ; Hanna Leontowicz^d ; Maria Leontowicz^d ; Zenon Jastrzebski^e ; Zev Tashma^f ; Shela Gorinstein^f ; ¹ ; ^{gorin@cc.huji.ac.il}
• 关键词：Indigo ; Bioactive compounds ; Antioxidant and antiproliferative activities
• 刊名：Lebensmittel-Wissenschaft und -Technologie
• 出版年：2012
• 出版时间：May 2012
• 年：2012
• 卷：46
• 期：2
• 页码：500-510
• 全文大小：1976 K

文摘

There are a few investigations on Indigo (Polygonum tinctorium Ait.), as a medicinal plant. Therefore, the aim of this study was to assess the contents of bioactive compounds, antioxidant and antiproliferative activities and to compare with another medicinal plant Prolipid. It was found that the bioactive compounds from different parts of Indigo water extracts varied (P < 0.05): polyphenols and flavonoids were significantly higher in Prolipid, flavanols in Indigo seeds, and vitamin C similar in Indigo leaves and Prolipid. The antioxidant activity by ABTS, FRAP, CUPRAC and DPPH assays was significantly different (P < 0.05): the highest in Prolipid, following by Indigo mature leaves. DPPH kinetic measurements compared, distinguished and discriminated the antiradical activity among Indigo and Prolipid water extracts by multivariate analysis. The interaction between polyphenol extracts of Indigo mature leaves and BSA showed that Indigo has a strong ability, as other medicinal plants, to quench the intrinsic fluorescence of BSA by forming complexes. In conclusion, for the first time Indigo mature leaves were analyzed and compared with widely consumed Prolipid. The relatively high content of bioactive compounds, positive antioxidant, fluorescence and antiproliferative properties of Indigo justify the use of this plant as a new source of valuable antioxidants.