Only minor changes in thrombin generation of children and adolescents with type 1 diabetes mellitus - A case-control study
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- 作者：Christina Cimenti ; christina.cimenti@medunigraz.at ; Axel Schlagenhauf ; Bettina Leschnik ; Elke Frö ; hlich-Reiterer ; Hildegard Jasser-Nitsche ; Harald Haidl ; Elisabeth Suppan ; Gudrun Weinhandl ; Maximilian Leberl ; Martin Borkenstein ; Wolfgang E. Muntean
- 关键词：aPTT ; activated partial thromboplastin time ; AT ; antithrombin ; CAT ; calibrated automated thrombography ; ETP ; endogenous thrombin potential ; F1 ; + ; 2 ; prothrombin fragments F1 ; + ; 2 ; FII ; prothrombin ; FVIII ; C ; factor VIII coagulant activity ; IDDM ; insulin-dependent diabetes mellitus ; NIDDM ; non-insulin-dependent diabetes mellitus ; PAI-1 ; plasminogen activator inhibitor type 1 ; PPP ; platelet-poor plasma ; PT ; prothrombin time ; TAT ; thrombin-antithrombin complex ; TF ; tissue factor ; T
- 刊名：Thrombosis Research
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：148
- 期：Complete
- 页码：45-49
- 全文大小：298 K
- 卷排序：148
文摘
Hypercoagulability might promote vascular disease in diabetes. Diabetic children show shorter lag time but decreased endogenous thrombin potential. Metabolic control, short disease duration or absent confounders might be causative.